CHANG, Shin Jae,KWON, Ki Sung,YI, Kye Sook,LEE, Hyun Joo,JEON, Jae Won,JUN, Hwang Keun,CHANG, Min Seok
申请号：
ES12835569
公开号：
ES2641257T3
申请日:
2012.09.27
申请国别(地区):
ES
年份:
2017
代理人:
摘要：
An antibody that has neutralizing activity against influenza A virus, comprising any polypeptide sequence selected from the group consisting of the following polypeptide sequences: a binding molecule composed of a light chain comprising, as determined according to the method of Kabat, a CDR1 region set forth in SEQ ID NO: 1, a CDR2 region set forth in SEQ ID NO: 2 and a CDR3 region exposed in SEQ ID NO: 3, and a heavy chain comprising, as determined by according to the Kabat method, a CDR1 region set forth in SEQ ID NO: 4, a CDR2 region set forth in SEQ ID NO: 5 and a CDR3 region set forth in SEQ ID NO: 6； a binding molecule composed of a light chain comprising, as determined in accordance with the Kabat method, a CDR1 region exposed in SEQ ID NO: 7, a CDR2 region exposed in SEQ ID NO: 8 and a CDR3 region set forth in SEQ ID NO: 9, and a heavy chain comprising, as determined according to the Kabat method, a CDR1 region set forth in SEQ ID NO: 10, a CDR2 region set forth in SEQ ID NO: 11 and a CDR3 region set forth in SEQ ID NO: 12； a binding molecule composed of a light chain comprising, as determined according to the Kabat method, a CDR1 region set forth in SEQ ID NO: 13, a CDR2 region exposed in SEQ ID NO: 8 and a CDR3 region set forth in SEQ ID NO: 9, and a heavy chain comprising, as determined according to the Kabat method, a CDR1 region set forth in SEQ ID NO: 10, a CDR2 region exposed in SEQ ID NO: 14 and a CDR3 region set forth in SEQ ID NO: 6； and a binding molecule composed of a light chain comprising, as determined according to the Kabat method, a CDR1 region set forth in SEQ ID NO: 15, a CDR2 region exposed in SEQ ID NO: 16 and a region CDR3 set forth in SEQ ID NO: 9, and a heavy chain comprising, as determined according to the Kabat method, a CDR1 region set forth in SEQ ID NO: 10, a CDR2 region set forth in SEQ ID NO: 17 and a CDR3 region set forth in SEQ ID NO: 12.Un anticuerpo que tiene actividad neutralizante contra el virus de la influenza A, que co
