The invention relates to methods for generating an aerosol by nebulization of a composition comprising polyclonal immunoglobulin (Ig). The selection of an efficient membrane nebulizer and a composition optimized for nebulization with such membrane nebulizer results in a particularly efficient method of generating an aerosol for administration of Ig to the respiratory tract.本發明關於藉由將包含多株免疫球蛋白(Ig)之組成物霧化來產生氣霧劑的方法。選擇有效之膜霧化器及經優化用於以此膜霧化器霧化的組成物可獲致特別有效之產生用於將Ig投予至呼吸道之氣霧劑的方法。