１Ｈ－吡唑并〔４，３－ｃ〕異喹啉衍生物、其製備及其於醫療上之應用农业专利-农业学术服务平台

发明人:: DELETTRE, GEORGES,迪里崔　乔治,迪里崔　喬治,DEPRETS, STEPHANIE,迪普瑞特　史蒂芬妮,HALLEY, FRANK,哈利　法兰克,哈利　法蘭克,SCHIO, LAURENT,斯区欧　劳伦特,斯區歐　勞倫特,THOMPSON, FABIENNE,汤普森　法比安,湯普森　法比安,迪里崔乔治,迪里崔喬治,迪普瑞特史蒂芬妮,哈利法兰克,哈利法蘭克,斯区欧劳伦特,斯區歐勞倫特,汤普森法比安,湯普森法比安

摘要：: The invention relates to a compound of formula (I):in which:‧Rlrepresents a phenyl group which is optionally substituted by one or more halogen atoms；‧R2represents:-　a hydrogen or halogen atom or a cyano group；-　a group -C(=O)Y in which Y represents a hydrogen atom or a group -NH2or -ORa；-　a group -C(=S)NH2；-　a group -C(=NH)NH-OH；-　a group -CH2OH or-CH2F；-　a group -CH=N-OH；-　a group -CH=CH2or-C≡C-Ra；-　a groupor；whereRarepresents a hydrogen atom or a (C1-C4)alkyl group；‧R3represents a hydrogen atom or a (C1-C4)alkyl group；‧ R4represents an -NH2, (C1-C4)alkyl, (C1-C4)fluoroalkyl or (C3-C7)cycloalkyl group.本發明係關於一種式(I)化合物：其中：‧R1代表苯基，其視情況經一或多個鹵素原子取代；‧R2代表：-　氫或鹵素原子或氰基；-　基團-C(=O)Y，其中Y代表氫原子或基團-NH2或-ORa；-　基團-C(=S)NH2；-　基團-C(=NH)NH-OH；-　基團-CH2OH或-CH2F；-　基團-CH=N-OH；-　基團-CH=CH2或-C≡C-Ra；-　基團或；其中Ra代表氫原子或(C1-C4)烷基；‧R3代表氫原子或(C1-C4)烷基；‧R4代表-NH2、(C1-C4)烷基、(C1-C4)氟烷基或(C3-C7)環烷基。