Seung Suh HONG,Shin Jae CHANG,Ki Sung KWON,Kye Sook YI,Sung Hwan KIM,Eun Beom LEE,Jae Won LEE,So Jung LEE,Ji Young SHIN,Myung Sam CHO
申请号：
US14780682
公开号：
US20160052997A1
申请日:
2014.03.28
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention provides a composition comprising at least two influenza A virus-neutralizing binding molecules that bind to an epitope in the stem region of influenza A virus hemagglutinin (HA) protein, the method comprising: i) a first binding molecule capable of neutralizing at least one influenza A virus subtype selected from the group consisting of H1, H2, H5 and H9； ii) a second binding molecule capable of neutralizing at least one influenza A virus subtype selected from the group consisting of H1, H3, H5, H7 and H9. The mixed composition of the present invention can effectively neutralize the multiple influenza subtypes of both phylogenetic group 1 and phylogenetic group 2 and can be used in combination with a chemical compound. Thus, the composition of the present invention is very useful for the prevention and treatment of a disease by influenza virus.
