The invention provides a process for the production of a monolithic implant for usein tissue engineering, the process comprising the steps of plasticising at leastone biocompatible material into a paste, extruding the paste through a die, anddrying the extruded material to eliminate an aqueous and/or non-aqueous component.The invention also relates to a monolithic implant as thereby manufactured, andthe use of such an implant as a scaffold for tissue-engineering and as a transplant tissuein reconstructive or replacement surgery.