The invention relates to a suture, which includes a thread body, and the outer peripheral surface of the thread body is cut by a spiral cutting method, so that a plurality of spiral grooves arranged at intervals are formed on the outer peripheral surface of the thread body. After cutting a spiral groove, a spiral protrusion for pulling the skin is formed one by one. Thereby, the suture of the present invention can increase the contact area with the skin, and can achieve the effects of reducing the cutting angle and enhancing the structural strength. In addition, the present invention further provides the aforementioned method of manufacturing a suture.本發明有關於一種縫線,其包含有一條線體,藉由螺旋切割方式對線體之外周面進行切割,使線體之外周面形成多個呈間隔排列之螺旋狀切槽,在完成每一個螺旋狀切槽的切割之後會一一對應地形成一個用來拉住皮膚之螺旋狀凸出物。藉此,本發明之縫線可以增加與皮膚之接觸面積,並且可以達到降低切削角度及提升結構強度的效果。另外,本發明更提供前述縫線的製造方法。