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Pharmaceutical form of administration, methods for its production and use
专利权人:
ZENTARIS GMBH
发明人:
BAUER HORST,DAMM MICHAEL,SARLIKIOTIS WERNER
申请号:
SK17162002
公开号:
SK288118B6
申请日:
2001.05.16
申请国别(地区):
SK
年份:
2013
代理人:
摘要:
A pharmaceutical form for the parenteral administration comprising dissolved or dispersed form of peptides prone to aggregation selected from cetrorelix, antarelix, antide, A-75998, ganirelix and Nal-Glu antagonist. In this form, the peptides are presented in the form of their acetate, gluconate, glucuronate, lactate, citrate, ascorbate, benzoate or phosphate salts, it is also present one of the just-mentioned acids as free acids, and, if appropriate, further additives and excipients from the class consisting of the acids, surface-active substances, polymers, lipids or sugars. It is described the form for use in the treatment of benign and malignant disease or for the treatment of sex hormone-dependent conditions.A pharmaceutical form for the parenteral administration comprising dissolved or dispersed form of peptides prone to aggregation selected from cetrorelix, antarelix, antide, A-75998, ganirelix and Nal-Glu antagonist. In this form, the peptides are presented in the form of their acetate, gluconate, glucuronate, lactate, citrate, ascorbate, benzoate or phosphate salts, it is also present one of the just-mentioned acids as free acids, and, if appropriate, further additives and excipients from the class consisting of the acids, surface-active substances, polymers, lipids or sugars. It is described the form for use in the treatment of benign and malignant disease or for the treatment of sex hormone-dependent conditions.
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