LUTOLF, MATTHIAS,SCHENSE, JASON CHARLES,JEN, ANNA,HUBBELL, JEFFREY ALAN
申请号：
CA2466116
公开号：
CA2466116C
申请日:
2002.11.07
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
Biomaterial comprises a three-dimensional polymeric network obtainable fromthe reaction of a at least a first and second precursor molecule. The firstprecursor molecule is at least a trifunctional, branched component comprisingat least three arms substantially similar in molecular weight and the secondprecursor molecule is at least a bifunctional component. The ratio ofequivalent weight of the funktional groups of the first and second precursormolecule is in a range of between 0.9 and 1.1. The molecular weight of thearms of the first precursor molecule, the molecular weight of the secondprecursor molecule and the functionality of the branching points are selectedso that the water content of the polymeric networks is between the equilibriumweight % and 92 weitht of the total weight of the polymeric network aftercompletion of water uptake. The present invention teaches a way to improvecharacteristics of synthetic matrices which are useful for wound healingapplications.
