Nanoparticle PEG modification with H-phosphonates

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专利权人:

Thomas E. Rogers

发明人:

Thomas E. Rogers

申请号：

US13599819

公开号：

US08889657B2

申请日:

2012.08.30

申请国别(地区):

US

年份:

2014

代理人:

摘要：

The present invention provides phosphonate conjugates and methods of preparing the phosphonate conjugates so as to allow, for example, improved methods and compounds for modifying the surface of a nanoparticle to increase in vivo circulation times and targeted delivery performance.

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