PROBLEM TO BE SOLVED: To provide a transdermal absorption sheet with which control of dissolution rate and suppression of drug diffusion can be achieved, and manufacturing method thereof.SOLUTION: A transdermal absorption sheet 100 includes: a sheet part 116； and a plurality of needle-like protrusions 110 comprising a plurality of frustum portions 114 disposed on the sheet part 116, and needle portions 112 disposed on the frustum portions 114. At least one of the needle-like protrusions 110 includes a hollow portion 124 extending from the sheet part 116 toward the frustum portion 114.SELECTED DRAWING: Figure 3COPYRIGHT: (C)2016,JPO&INPIT【課題】溶解速度の制御と薬剤の拡散の抑制とを達成できる経皮吸収シート、及びその製造方法を提供する。【解決手段】経皮吸収シート１００は、シート部１１６と、シート部１１６の上に配置された複数の錐台部１１４と、錐台部１１４の上に配置されたニードル部１１２とで構成される複数の針状凸部１１０とを備え、針状凸部１１０の少なくとも一つがシート部１１６から錐台部１１４に延びる空洞部１２４を有する。【選択図】図３
