In the present invention, provided is a technique of loading a biopsy device to perform one time tissue taking and multiple times tissue taking at one time without changing a gripping way while gripping the biopsy device with one hand, and enabling to easily collect the taken tissues. According to one embodiment of the present invention, a disposable cutting biopsy device comprises: a housing which is extended in a parallel direction with one axis and has a hollow part inside; a needle set which comprises an inner needle inserted and fixed in the housing through a first directional one side hole of the housing and having a tissue taking groove, and an outer needle having a blade on a tip end to cut a tissue received in the tissue taking groove and performing a reciprocating motion based on the inner needle by forming a needle tube containing the inner needle therein; a master block which is in connection with one side of the outer needle in a second direction opposite to the first direction based on one axis, has the length in a parallel direction with the one axis longer than the length in an orthogonal direction with the one axis, and is arranged to perform a reciprocating motion in the hollow part in a parallel direction with the one axis; a driving unit which is in connection with the master block and has a first spring, a hub block with a needle set penetration unit, and a second spring that are successively arranged in a line and connected in the hollow part; and a loading unit which comprises a loading connector installed to vary a position to be hooked on the hub block and a loading handle in connection with the loading connector to apply force of a second direction to the loading connector.생검기구를 파지한 한손만으로 파지 형태의 변경 없이 1회 채취와 복수회 채취를 한 번에 수행할 수 있도록 생검기구를 장전하는 것과, 채취된 조직을 쉽게 회수 가능하도록 하는 기술을 제공한다. 본 발명의 일 실시예에 따른 일회용 절단 생검기구는, 일 축과 평행한 방향으로 연장형성되어 있으며 내부에 중공부가 형성된 하우징; 하우징의 제1 방향 단측 홀을 통하여 하우징 내부에 삽입 고정되어 있으며 조직채취홈이 형성된 속침과, 조직채취홈에 수용된 조직을 절단하도록 선단에 날이 형성되어 있으