An isolated novel Lactobacillus paracasei K66 is provided. Lactobacillus paracasei K66 has features of faster proliferation and excellent acid production, has abilities to secret extracellular polysaccharide, to resist bile salt and gastric acid, and to regulate immunity, inflammation and allergy, and is adequate to be an additive in a fermented product, a functional product or dairy food.本發明係關於一種新穎副乾酪乳桿菌副乾酪亞種(Lactobacillus paracasei subsp.paracasei)K66。此菌株增殖快速且產酸能力優異,具有分泌胞外多醣以及對抗膽鹽和胃酸侵襲的能力,更可調節免疫、過敏和發炎現象,十分適合作為醱酵產品、功能性食品和乳製品的添加物。本案圖式均為實驗數據圖式,故無指定代表圖