Kodra, Janos Tibor,Tagmose, Tina Moller,Kjeldsen, Thomas Borglum,Garibay, Patrick William,Jakobsen, Palle,Madsen, Peter,Gram, Dorte Xenia,Hoeg-Jensen, Thomas
申请号：
AU2008288413
公开号：
AU2008288413B2
申请日:
2008.08.15
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
An acylated insulin analogue wherein the insulin analogue comprises a lysineresidue connected C-terminally to the A21 amino acid residue or a peptide residueof up to 4 amino acid residues comprising a lysine residue which peptide residueis connected C-terminally to the A21 amino acid residue, characterized in thatan acyl moiety comprising an alkylene glycol moiety is attached to the lysineresidue in the A22 position or attached to a lysine residue present in the peptideresidue that is attached to the C terminal end of the A21 amino acid residue andwherein there is only one lysine (K, Lys) in the insulin analogue, can convenientlybe administered pulmonary.
