超音波媒介デリバリー用ガス充填マイクロカプセル含有医薬組成物

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专利权人:

ブラッコ・シュイス・ソシエテ・アノニム

发明人:

ティエリー・ベタンジェ,フェン・ヤン,ソフィー・メイエ-ウンベール,ペーテル・フリンキング

申请号：

JP2008507051

公开号：

JP5049958B2

申请日:

2006.04.11

申请国别(地区):

JP

年份:

2012

代理人:

摘要：

Composition comprising gas filled microcapsules and a bioactive agent, useful for an ultrasound-mediated delivery of said bioactive agent. The microcapsules comprise a relatively stiff shell of polymeric or lipid material and have in particular a resistance to a mechanical index of at least 0.15, while the bioactive agent is substantially unbound to the shell of the microcapsules. The composition of the invention is particularly suitable for effectively delivering a genetic material into a cell, upon exposure of the composition to a level of acoustic pressure capable of destroying a portion of the microcapsules and releasing the gas contained therein.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/