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COMPOSITION FOR INDUCING DIFFERENTIATION OF CARDIOMYOCYTES CONTAINING ECHINOCHROME A AS ACTIVE INGREDIENT
专利权人:
INJE UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION;인제대학교 산학협력단
发明人:
HAN, JINKR,한진,HEO, HYE JINKR,허혜진,KIM, NA RIKR,김나리,KIM, HYOUNG KYUKR,김형규,HAN, JIN,HEO, HYE JIN,KIM, NA RI,KIM, HYOUNG KYU
申请号:
KR1020160026942
公开号:
KR1020170104223A
申请日:
2016.03.07
申请国别(地区):
KR
年份:
2017
代理人:
摘要:
The present invention relates to a pharmaceutical composition for promoting differentiation of cardiomyocytes derived from embryonic stem cells containing echinochrome A as an active ingredient. More specifically, echinochrome A extracted from echinoderm such as sea urchins does not cause cytotoxicity, and also effectively induces differentiation into cardiomyocytes in mouse embryonic stem cells. According to the present invention, the composition containing the echinochrome A as the active ingredient can be provided as culture medium compositions or compositions for inducing cardiomyocyte differentiation.COPYRIGHT KIPO 2017본 발명은 에키노크롬 A(Echinochrome A)를 유효성분으로 함유하는 배아줄기세포 유래 심근세포 분화촉진용 약학조성물에 관한 것으로, 보다 상세하게는 극피동물 성게류에서 추출된 에키노크롬 A는 세포독성을 나타내지 않으며 생쥐 배아줄기세포에서 심근세포로의 분화를 효과적으로 유도하는 것으로 확인됨에 따라 본 발명에 따른 에키노크롬 A를 유효성분으로 함유하는 조성물은 심근세포 분화유도용 조성물 또는 배지조성물로 제공될 수 있다.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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