POPEK, TOMASZ,PATEL, KISHORE,ALAKHOV, VALERY,PIETRZYNSKI, GRZEGORZ
申请号：
EP10745872
公开号：
EP2400987A4
申请日:
2010.02.24
申请国别(地区):
EP
年份:
2012
代理人:
摘要：
The present invention is directed to pharmaceutical compositions comprising: (a) bendamustine, (b) a charged cyclopolysaccharide, and (c) a stabilizing agent having a charge opposite to that of the cyclopolysaccharide. Such composition provides unexpectedly desirable stability in reactive environments such as plasma, coupled with unexpectedly desirable anticancer activity. Such compositions are suitable for injection or infusion into patients in need for treatment with bendamustine.
