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Orally disintegrating sheet preparation
专利权人:
株式会社ダイセル
发明人:
上友 淳弘,岡林 智仁,橋川 尚弘
申请号:
JP2015237929
公开号:
JP6615595B2
申请日:
2015.12.04
申请国别(地区):
JP
年份:
2019
代理人:
摘要:
PROBLEM TO BE SOLVED: To provide an oral disintegrating sheet-shaped pharmaceutical preparation which has sufficient strength even if containing no calcium silicate and which has excellent disintegration properties.SOLUTION: The present invention relates to a production method of an oral disintegrating sheet-shaped pharmaceutical preparation with a thickness of less than 5 mm which is obtained by compression molding, wherein the intraorally disintegrating time is preferably 20 seconds or less and the sheet strength is 0.04 N or more. Preferably, the oral disintegrating sheet-shaped pharmaceutical preparation contains one or more ingredients selected from crospovidone, croscarmellose sodium, low substituted hydroxypropylcellulose and carboxy methyl starch, as a disintegrant, and one or more ingredients selected from D-mannitol, lactose, trehalose, cellulose, xylitol and calcium phosphate, as an excipient.SELECTED DRAWING: None
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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