Igawa, Tomoyuki,Kadono, Shojiro,Hironiwa, Naoka,Sakurai, Mika
申请号:
AU2014347565
公开号:
AU2014347565A1
申请日:
2014.11.11
申请国别(地区):
AU
年份:
2016
代理人:
摘要:
The inventors have succeeded in creating an antigen-binding molecule containing an antibody variable region, the molecule having binding activity to a molecule expressed on the surface of T cells and to a molecule expressed on the surface of another immune cell, but not binding simultaneously to both. The present invention enables the creation of an antigen-binding molecule that can prevent side effects that can occur when T cells and other immune cells crosslink, and provides an antigen-binding molecule that is suitable as a drug.