Gilwoo CHOI,Leo GRADY,Charles A. TAYLOR,Stanley C. HUNLEY
申请号:
US15267671
公开号:
US20170076062A1
申请日:
2016.09.16
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Systems and methods are disclosed for providing personalized chemotherapy and drug delivery using computational fluid dynamics and medical imaging with machine learning from a vascular anatomical model. One method includes receiving a patient-specific anatomical model of at least one vessel of the patient and a target tissue where a drug is to be supplied; receiving patient-specific information defining the administration of a drug; deriving patient-specific data from the patient specific anatomical model and/or the patient; determining one or more blood flow characteristics in a vascular network leading to the one or more locations in the target tissue where drug delivery data will be estimated or measured, using the patient-specific anatomical model and the patient-specific data; and computing drug delivery data at the one or more locations in the target tissue using transportation, spatial, and/or temporal distribution of the drug particles.