ADENOVIRAL VECTORS COMPRISING PARTIAL DELETIONS OF E3

• 收藏
• 分享

专利权人:

THE WISTAR INSTITUTE

发明人:

Hildegund C.J. ERTL,Xiang Yang Zhou

申请号：

US15453579

公开号：

US20170175138A1

申请日:

2017.03.08

申请国别(地区):

US

年份:

2017

代理人:

摘要：

This disclosure provides replication-incompetent adenoviral vectors useful in vaccine development and gene therapy. The disclosed vectors comprise a selective deletion of E3 and are particularly useful for preparation of vaccines development and for gene therapy using toxic transgene products that result in vector instability that occurs when the entire E3 domain is deleted.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/