Toshio KAWANAMI;Muneto MOGI;Robert SUN;Nikolaus SCHIERING;Rajeshri Ganesh KARKI;Qian LIU;Gary Michael KSANDER
发明人:
Rajeshri Ganesh KARKI,Toshio KAWANAMI,Gary Michael KSANDER,Qian LIU,Muneto MOGI,Nikolaus SCHIERING,Robert SUN
申请号:
US13293560
公开号:
US20120122764A1
申请日:
2011.11.10
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention provides a compound of formula I;or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, B, X, m and n are defined herein. The invention also relates to a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides pharmaceutical composition of compounds of the invention, and a combination of pharmacologically active agents and a compound of the invention.