#$%^&*AU2009212946B220130725.pdf#####ABSTRACT The present invention relates to a method for the effective treatment of tissue defects and for tissue regeneration. The method includes seeding autologous cells on a support matrix and implanting the cell-seeded support matrix into a site of transplantation. The present invention also relates to various 5 tissue repair structures that include cells seeded onto a cell-free membrane. The present invention also provides methods for cultivation, seeding and implantation of autologous cells.