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Phosphohistidine analogs
专利权人:
Tom W. Muir
发明人:
Tom W. Muir,Jung-Min Kee
申请号:
US13825699
公开号:
US09035068B2
申请日:
2011.09.23
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates to the phosphohistidine analogs of the present invention which of the formula (I) and the hapten containing the residue of same. It also relates to the hapten conjugated to a carrier molecule and the isolated antibodies raised against the immunogens, said antibodies recognizing polypeptide containing a phosphorylated histidine or the phosphotriazole residue but it does not recognize an amino acid or polypeptide that is not phosphorylated or a polypeptide which is phosphorylated on amino acids other than histidine but not on histidine.
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