Gordon Kim Prisk,Susan Roberta Hopkins,Richard Bruce Buxton,Rui Carlos Pereira De Sá,Rebecca Jean Theilmann,Matthew Vincent Cronin
申请号：
US13992231
公开号：
US09750427B2
申请日:
2011.12.07
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Methods, devices, and systems are disclosed for implementing a fully quantitative non-injectable contrast proton MRI technique to measure spatial ventilation-perfusion (VA/Q) matching and spatial distribution of ventilation and perfusion. In one aspect, a method using MRI to characterize ventilation and perfusion in a lung includes acquiring an MR image of the lung having MR data in a voxel and obtaining a breathing frequency parameter, determining a water density value, a specific ventilation value, and a perfusion value in at least one voxel of the MR image based on the MR data and using the water density value to determine an air content value, and determining a ventilation-perfusion ratio value that is the product of the specific ventilation value, the air content value, the inverse of the perfusion value, and the breathing frequency.
