Systems and methods are described to determine a region of interest, determine a first beam steering angle of a first ultrasound beam transmitted from an ultrasound transducer array that results in a maximum representative signal value received from the region of interest, determine a second beam steering angle based on the first beam steering angle, the second beam steering angle being closer to perpendicular with the ultrasound transducer array than the first beam steering angle, and acquire an ultrasound image using a beam transmitted from the ultrasound transducer array at the second beam steering angle.