Compounds and methods for improving cellular uptake of oligomeric compounds

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专利权人:

Isis Pharmaceuticals; Inc.

发明人:

Erich Koller,C. Frank Bennett

申请号：

US13658544

公开号：

US08999951B2

申请日:

2012.10.23

申请国别(地区):

US

年份:

2015

代理人:

摘要：

The present invention provides method of optimizing the efficacy and potency of antisense drugs. In certain embodiments, the invention provides assays useful for determining favorable oligonucleotide characteristics and excipients for improved cellular uptake.

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