Sang Ho CHOI,Lak Shin JEONG,Ho Jae HAN,Nam Chul HA,Byoung Sik KIM,Kyung Ku JANG,Zee-Won LEE
申请号:
US16637053
公开号:
US20200237718A1
申请日:
2019.01.07
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Provided is a method for treating a symptom of vibrio infection by using an RTX toxin production inhibitor comprising N-(4-oxo-4H-thieno[3,4-c]chromen-3-yl)-3-phenylprop-2-ynamide having derivatives thereof which can repress (prevent or treat) a symptom of vibrio infection by inhibiting RTX toxin production, other than directly killing vibrio bacteria, to not allow vibrio bacteria to have pathogenicity, and thereby can be an alternative to antibiotics that aim to kill bacteria themselves and thus fundamentally retain the problem of resistance incurrence.