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HIGHLY IMMUNOGENIC HIV P24 SEQUENCES
专利权人:
LABORATORIOS DEL DR. ESTEVE; S.A.
发明人:
MOTHE PUJADAS, BEATRIZ,BRANDER, CHRISTIAN,MULLINS, JAMES I.
申请号:
CA2817418
公开号:
CA2817418A1
申请日:
2011.11.10
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The invention relates to peptides comprising part or all of a conserved element within a Center-of-Tree (COT) sequence derived from a family of polypeptides encoded by naturally occurring variants of HIV. The invention also relates to immunogenic compositions and vaccines comprising said peptides. The invention also relates to methods for the identification of HIV controller patients based on the detection of the T cells of the patient to mount a cytotoxic T cell response against said peptides and to methods for the identification of immunogenic peptides within a family of variant polypeptides.
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