The Trustees of Columbia University in the City of New York
发明人:
Elizabeth M.C. HILLMAN
申请号：
US16303017
公开号：
US20190317312A1
申请日:
2017.05.30
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Implementing swept, confocally aligned planar excitation (SCAPE) imaging with asymmetric magnification in the detection arm provides a number of significant advantages. In some preferred embodiments, the asymmetric magnification is achieved using cylindrical lenses in the detection arm that are oriented to increase the magnification of the intermediate image in the width direction but not in the depth direction. SCAPE imaging may also be improved by using an SLM to modify a characteristic of the sheet of excitation light that is projected into the sample. Additional embodiments include a customized version of SCAPE that is optimized for imaging the retina at the back of an eyeball in living subjects.
