PROBLEM TO BE SOLVED: To provide pharmaceuticals, cosmetics or the like having filaggrin production promoting action, and exhibiting skin moisture retention and natural moisture-retaining factor production promoting effects, or material blended in the same.SOLUTION: A filaggrin production promoter comprises a lignan represented by the general formula (1), where R is a hydrogen atom or a C1-10 alkoxy group, as an active ingredient.COPYRIGHT: (C)2015,JPO&INPIT【課題】フィラグリン産生促進作用を有し、皮膚保湿、天然保湿因子産生促進効果を発揮する医薬品、化粧品等、或いはこれらに配合する素材の提供。【解決手段】 下記一般式(1)〔式中、Rは水素原子又は炭素数1-10のアルコキシ基を示す。〕で表されるリグナン類を有効成分とするフィラグリン産生促進剤。【選択図】なし
