DERIVES D'ADENOSINE, PROCEDE POUR LA SYNTHESE DE CES DERNIERS, ET COMPOSITIONS PHARMACEUTIQUES POUR LA PREVENTION ET LE TRAITEMENT DE MALADIES INFLAMMATOIRES CONTENANT LESDITS DERIVES EN TANT QU'INGREDIENTS ACTIFS
FM THERAPEUTICS CO., LTD.;GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
发明人:
JEONG, LAK SHIN,KIM, HEA OK,JACOBSON, KENNETH A.,CHOE, SEUNG AH
申请号:
CA2680179
公开号:
CA2680179C
申请日:
2007.03.07
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
Adenosine derivatives, synthetic methods therefor, and pharmaceuticalcompositions for theprevention and treatment of inflammatory diseases are provided. The activeingredient mayinclude the following Chemical formula 1:(see formula 1)wherein, A is O or S, R is a linear or branched C1~C5 alkyl which is non-substituted or isindependently or selectively substituted with one or more C6~C10 aryl groups,a benzyl which isnon-substituted or is independently or selectively substituted with halogen orone or more linearor branched C1 ~ C4 alkoxy groups, or a hydroxycarbonyl-substituted benzyl;and Y is H or ahalogen atom.