Setiady, Julianto,Singh, Rajeeva,Park, Peter U.,Rui, Lingyun,Chittenden, Thomas
申请号：
AU2011320318
公开号：
AU2011320318B2
申请日:
2011.10.28
申请国别(地区):
AU
年份:
2015
代理人:
摘要：
The disclosure provides anti-cancer agents, including, but not limited to, antibodies and immunoconjugates, that bind to EGFR. Specifically, the disclosure provides anti-EGFR antibodies and fragments thereof which do not inhibit EGFR signaling but are highly cytotoxic to EGFR overexpressing tumor cells. The methods of using the agents, antibodies, or immunoconjugates, for inhibiting tumor growth are also provided.
