Коригодский Александр Робертович (RU),Захаров Иван Дмитриевич (RU)
申请号:
RU2013127608/15
公开号:
RU2013127608A
申请日:
2013.06.18
申请国别(地区):
RU
年份:
2014
代理人:
摘要:
1. A medicament for the treatment of keratoconus and other degenerative corneal diseases containing as an active ingredient an effective amount of the amine with the functional groups in salt form or in complex compound of a transition metal or smesi.2. A medicament according to claim 1, characterized in that the amine-functional groups using amino alcohols or amino acids or amino acid derivatives or oligopeptides, or polypeptides, or polyamines or derivatives of 3-hydroxy-2-methylpyridine, or aminosaharidy or smes.3. A medicament according to claim 2, characterized in that the aminoalcohol is 2-amino-2-methyl-1,3-propanediol or tris (hydroxymethyl) aminomethane or smes.4. A medicament according to claim 2, characterized in that the amino acids are used as 2,4-diaminobutanoic acid, or ornithine, or lysine, or hydroxylysine, or 2,7-diaminogeptanovuyu acid, or 2,8-diaminooktanovuyu acid, or 2.9 -diaminononanovuyu acid, or 2,10-diaminodekanovuyu acid, or 2,12-diaminododekanovuyu acid, or arginine or smes.5. A medicament according to claim 4, characterized in that as amino acids are used D- or L-optical isomers of amino acids or their D, L-mixture (racemate) .6. A medicament according to claim 2, characterized in that as amino acid derivatives using one of the amino lactam of claims 4 and 5, or an amino acid mixture of lactams of claims 4 and 5.7. A medicament according to claim 2, characterized in that as amino acid derivatives using one ester of amino acids according to claim 4 and 5 or a mixture of amino acid esters according to claims 4 and 5.8. medicinal Wed1. Лекарственное средство для лечения кератоконуса и других дегенеративных заболеваний роговицы, содержащее в качестве активного компонента эффективное количество амина с функциональными группами в виде соли или в составе комплексного соединения переходного металла или их смеси.2. Лекарственное средство по п.1, отличающееся тем, что в качестве амина с функциональными группами используют аминоспирты, или аминокис