Disclosed herein is a plant of the genus cannabis that does not require flowering in order to produce trichomes comprising secondary compounds. Provided herein is a plant of the genus cannabis that has trichomes on non-flowering parts of the plant, such as leaves. The disclosed plants have a high mass % of secondary compounds and a high degree of trichome coverage on the surface of the plant. Also disclosed herein are methods of producing secondary compounds from a plant of genus cannabis without flowering the plant of genus cannabis. For example, the disclosed methods provide for inducing trichome development on a plant of genus cannabis without flowering the plant of genus cannabis.