The invention relates to a composition comprising 2% to 5% minoxidil, 0.01% to15%finasteride and 0.01% to 15% of a prostaglandin analogue. In one embodiment,the prostaglandinanalogue is latanoprost. I a preferred embodiment, the composition comprises5% minoxidil,0.1% finasteride and 0.03% latanoprost. The invention also relates to the useof the saidcomposition to reduce hair loss and/or increase regrowth of hair in a humansubject.