Described herein is a method of producing a tissue graft, comprising at least:providing a gel,seeding the gel with endothelial cells and fibroblast or SVF cells, culturingsaid endothelial cellsand fibroblasts or said SVF cells in and/or on said gel until the formation ofat least a vascularstructure in and/or on said gel by said endothelial cells and fibroblast orsaid SVF cells, compactingthe gel after formation of said vascular structure, seeding keratinocytes ontothe gel aftercompaction of said gel , and culturing said keratinocytes in and/or on saidgel until the formationof an epidermal structure on said gel. A related tissue graft is alsodisclosed. The method or tissuegraft disclosed herein may be used in the treatment of damaged skin.
