ANDRÉ GONÇALVES BEZERRA JUNIOR,DARLYSON TAVARES GUIMARÃES,MARCUS VINICIUS LIA FOOK,ROSSEMBERG CARDOSO BARBOSA,VENTURIELSO VENTURA GOMES,WLADYMYR JEFFERSON BACALHAU DE SOUSA
申请号：
BR102017019727
公开号：
BR102017019727A2
申请日:
2017.09.15
申请国别(地区):
BR
年份:
2019
代理人:
摘要：
Scaffold for intravaginal clearance of Fenticonazole in the treatment of fungal vaginitis. This invention deals with scaffold manufacture for intravaginal clearance of Fenticonazole in the treatment of fungal vaginitis, scaffold composite is composed of chitosan /fenticonazole /gelatine in the form of capsules obtained by the lyophilisation method. Fungal vaginitis is a p Infectious and /or inflammatory process of the female lower genitourinary tract relevant to theMedicine due to the high number of appointments in gynecology offices. The symptomatology of fungal vulvovaginitis is not pathogenic and clinical suspicion can be confirmed by tests that show the nature of the etiological agentBeing more frequent in women between 18 and 34 years of age. For the correct diagnosis, women complaining of vaginal symptomatology should be subject to the standard assessment of vaginal pH, whiff test, fresh microscopy and potassium hydroxide (koh) to 10%. For the treatment of candidiasis antifungal agents are used orally and vaginally in the form of capsule and cream respectively. The encapsulation of antifungal agents in drug release systems has been used to change the agent's pharmacokinetics,Enabling more effective treatments with lower incidence of side effects. The use of biodegradable polymers, such a s chitosan and gelatine for intravaginal ova (scafollds) for drug release have great potential in the most diverse types of treatment such a s fungal vaginitis.scaffold para liberação intravaginal de fenticonazol no tratamento da vaginite fúngica. a presente invenção trata da fabricação scaffold para liberação intravaginal de fenticonazol no tratamento de vaginite fúngica, o compósito de scaffold é constituído de quitosana/fenticonazol/gelatina em forma de capsulas obtidos pelo método de liofilização. a vaginite fúngica é um processo infeccioso e/ou inflamatório do trato geniturinário inferior feminino relevante na medicina devido ao acentuado número de atendimentos em consult
