A bio-impedance measurement apparatus includes a flexible band member, two probe sets attached to the flexible band member, a measurement device, and a wireless device. One probe set includes a probe having a tip portion configured to pierce the skin for an acupuncture point. Another probe set, used as an electrical ground, includes a probe configured to contact the reference skin at a region. The measurement device is disposed on the flexible band member and electrically coupled to the two probe sets for provision of an impulse current signal to the acupuncture point. The measurement device can amplify and measure the voltage response across the acupuncture points and the ground. The amplified signal is converted to a digital signal. The wireless device is configured to transmit the acupuncture code and impedance information to a remote monitor station. The bio-impedance measurement apparatus is disposed on a wearable sock or glove.
