PROBLEM TO BE SOLVED: To provide a novel pharmaceutical formulation for reducing frequency of urination.SOLUTION: The present invention provides the use of acetaminophen and ibuprofen in production of a pharmaceutical formulated for oral administration to reduce the frequency of urination, each content of acetaminophen and ibuprofen being 50 mg to 500 mg, the pharmaceutical is blended for immediate release, delayed release, extended release or a combination thereof, the pharmaceutical contains a lubricant, and acetaminophen and ibuprofen are only therapeutic active ingredients in the pharmaceutical.SELECTED DRAWING: Figure 1COPYRIGHT: (C)2020,JPO&INPIT【課題】排尿の頻度を低下させるための新規医薬組成物の提供。【解決手段】排尿の頻度を低下させるための経口投与用に製剤化された医薬品の製造におけるアセトアミノフェン及びイブプロフェンの使用であって、アセトアミノフェン及びイブプロフェンの夫々を５０ｍｇから５００ｍｇの量で含み、該医薬品が即時放出、遅延放出、延長放出又はそれらの組み合わせ用に配合され、更に、該医薬品は滑剤を含み、かつ、アセトアミノフェン及びイブプロフェンのみが該医薬品中の治療上の有効成分である、前記使用。【選択図】図１
