ГЕЙВИН Пол Дейвид (AU),ЭЛЬ-ТАМИМИ Махмуд (AU),КОТРЕЛЛ Джереми Джеймс (AU),ГАЭТАНО Джасинто (AU),КЕННЕДИ Николас Джон (AU)
申请号:
RU2012126143/15
公开号:
RU2012126143A
申请日:
2010.12.22
申请国别(地区):
RU
年份:
2014
代理人:
摘要:
1. A carrier composition for delivering a biologically active compound containing a phosphate compound as an electron transfer agent and a polar proton solvent selected from the group consisting of acyclic alcohols, alkyl esters, ketones and nitriles, in which the concentration of the polar proton solvent is about 60- 90% of the mass. total concentration of carrier composition. 2. The carrier composition according to claim 1, wherein the concentration of the polar proton solvent is about 65-85% by weight, about 70-80% by weight, or about 50-60% by weight, or about 60-70% by weight, or about 80-90% of the mass. 3. A carrier composition according to claim 1, wherein the polar protic solvent is an acyclic alcohol. The carrier composition according to claim 3, in which the acyclic alcohol is selected from the group consisting of C-C-acyclic alcohols, polyols of C-C-acyclic alcohols, polymers of C-C-acyclic alcohols and esters, alkyl esters and their derivatives of ethers. The carrier composition according to claim 3, wherein the acyclic alcohol is ethanol, n-propanol, isopropanol, ethylene glycol, propylene glycol, polyethylene glycol, diethylene glycol monoethyl ether or ethyl acetate. A carrier composition according to claim 1, wherein the polar protic solvent is a ketone. A carrier composition according to claim 6, in which the ketone is methyl isobutyl ketone or acetone. A carrier composition according to claim 1, wherein the polar protic solvent is nitrile. The carrier composition of claim 8, in which the nitrile is acetonitrile. The carrier composition according to claim 1, wherein the electron transfer agent is hydroxychroman. The carrier composition of claim 10, wherein1. Композиция носителя для доставки биологически активного соединения, содержащего фосфатное соединение в качестве агента переноса электронов и полярный протонный растворитель, выбранный из группы, состоящей из ациклических спиртов, сложных алкильных эфиров, кетонов и нитрилов, в которой концентра