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Controlled Release and Taste Masking Oral Pharmaceutical Composition
专利权人:
Massimo PEDRANI;Roberto VILLA;Mauro AJANI;Lorenzo FOSSATI
发明人:
Roberto VILLA,Massimo PEDRANI,Mauro AJANI,Lorenzo FOSSATI
申请号:
US13462430
公开号:
US20120220559A1
申请日:
2012.05.02
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Controlled release and taste masking compositions containing one or more active principles inglobated in a three-component matrix structure, i.e. a structure formed by successive amphiphilic, lipophilic or inert matrices and finally inglobated or dispersed in hydrophilic matrices. The use of a plurality of systems for the control of the dissolution of the active ingredient modulates the dissolution rate of the active ingredient in aqueous and/or biological fluids, thereby controlling the release kinetics in the gastrointestinal tract.
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