A composition comprising:(a) one to three bioactive agents and(b) a vehicle comprising(i) a modified liquid carrier, and(ii) an unmodified liquid carrierwherein the ratio by volume of the modified liquid carrier to the unmodified liquid carrier is between 0.00001:99.99999 to less than 0.01:99.99, that provide the composition with predictable sustained-release properties and wherein immediately after manufacture of the composition, said composition can be administered to a host such that the one to three bioactive agents is released to the host on a sustained basis.