RAJEEV, KALLANTHOTTATHIL G.,ZIMMERMANN, TRACY,MANOHARAN, MUTHIAH,MAIER, MARTIN,FITZGERALD, KEVIN
申请号：
CA2812046
公开号：
CA2812046A1
申请日:
2011.09.14
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
The present invention provides effective motifs for RNA agents conjugated to at least one ligand, which are advantageous for the in vivo delivery of iRNA duplex agents. Additionally, the present invention provides methods of making these compositions, as well as methods of introducing these iRNA duplex agents into cells using these compositions, e.g., for the treatment of various disease conditions.
