DERIVADOS DE 2-HIDROXI-1-{4-[(4-FENILFENIL)CARBONIL]PIPERAZIN-1-IL}ETANO-1-ONA E COMPOSTOS RELACIONADOS COMO INIBIDORES DA SINTASE DE ÁCIDOS GORDOS (FASN) PARA O TRATAMENTO DO CANCRO
DAVID R. LANCIA, JR.,KENNETH W. BAIR,HONGBIN LI,JAMES LOCH,WEI LU,MATTHEW W. MARTIN,DAVID S. MILLAN,SHAWN E.R. SCHILLER,MARK J. TEBBE
申请号：
PT14779048
公开号：
PT2968316T
申请日:
2014.03.11
申请国别(地区):
PT
年份:
2019
代理人:
摘要：
The present invention relates to a list of specific 2-hydroxy-1-{4-[(4-phenylphenyl)carbonyl]piperazin-1-yl}ethan-1-one derivatives and related compounds as fatty acid synthase (FAS or FASN) inhibitors for treating cancer and pharmacutical compositions thereof .An illustrative compound of the invention is shown below:
