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Ipamorelin diacetate injection and infusion solutions
专利权人:
HELSINN THERAPEUTICS (U.S.) INC.
发明人:
RUBIO SILVINA GARCIA,WEIBEL HELLE,BRAGLIA RICCARDO,BEIDLER DANIEL
申请号:
NZ59664110
公开号:
NZ596641A
申请日:
2010.05.27
申请国别(地区):
NZ
年份:
2013
代理人:
摘要:
596641 Disclosed is an injection or infusion solution of Ipamorelin comprising: a) ipamorelin solubilized by approximately two molar equivalents of acetic acid (ipamorelin diacetate), in an amount of from 0.001 to 20%, based on the weight of the free base of ipamorelin; b) a molar excess of acid, preferably acetic acid, in an amount sufficient to give a pH of at least 4 and less than 6.5; c) optionally from 0.1 to 30% of one or more formulation aids; and d) water q.s. to 100%; all percentages based on the total weight of the solution. Also disclosed are methods for the production of such a solution.
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中国工程科技知识中心
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