MITOMO KATSUYUKI C/O ID PHARMA CO. LTD,INOUE MAKOTO C/O ID PHARMA CO. LTD.,IWASAKI HITOSHI C/O ID PHARMA CO. LTD.,HASEGAWA MAMORU C/O ID PHARMA CO. LTD,ALTON ERIC W,GRIESENBACH UTA,MITOMO Katsuyuki c/o ID Pharma Co. Ltd,INOUE Makoto c/o ID Pharma Co. Ltd.,IWASAKI Hit
申请号：
SI200632015
公开号：
SI1950307T1
申请日:
2006.10.27
申请国别(地区):
SI
年份:
2016
代理人:
摘要：
The present inventors successfully introduced genes into stem cells of airway epithelial tissues using simian immunodeficiency virus vectors pseudotyped with F and HN, which are envelope glycoproteins of Sendai virus. Gene transfer into airway epithelial tissue stem cells using a vector of the present invention is useful for gene therapy of genetic respiratory diseases such as cystic fibrosis. Furthermore, it is possible to select respiratory organs such as the lungs as production tissues for providing proteins that are deficient due to genetic diseases.
