HADIDA-RUAH SARA SABINA,KALLEL EDWARD ADAM,ARUMUGAM VIJAYALAKSMI,MILLER MARK THOMAS,DENINNO MICHAEL PAUL,ZHOU JINGLAN,UY JOHNNY,FRIEMAN BRYAN A.
申请号：
NZ62725913
公开号：
NZ627259A
申请日:
2013.01.15
申请国别(地区):
NZ
年份:
2016
代理人:
摘要：
Disclosed are pyran spirocyclic piperidine amide compounds of formula (I), wherein the substituents are as defined in the specification. The compounds are useful as inhibitors of sodium ion channels in the treatment of various disorders and conditions. Examples of a compound of formula (I) are: [cis-8-hydroxy-10-phenyl-11-oxa-3-azaspiro[5,5]undecan-3-yl]-(4-isopropoxy-3-methyl-phenyl)methanone (4-isopropoxy-3-methy1-phenyl)-[cis-8-isopropoxy-10-phenyl-11-oxa-3-azaspiro[5,5]undecan-3-yl]methanone
