SOANE, DAVID S.,WUTHRICH, PHILIP,MAHONEY, ROBERT P.,NAIK, SUBHASHCHANDRA,TRAN, TIMOTHY,PORTILLA, ROSA CASADO,GREENE, DANIEL G.,PORTILLA, ROSA CARADO
申请号:
CA3091931
公开号:
CA3091931A1
申请日:
2019.03.05
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
Disclosed herein are stability-enhanced formulations that comprise a therapeutic protein and a stability-improving amount of a stabilizing excipient, wherein the stabilized- enhanced formulation is characterized by an improved stability parameter in comparison to a control formulation otherwise identical to the stability -enhanced formulation but lacking the stabilizing excipient. Further disclosed herein are methods of improving stability of therapeutic formulations or improving parameters of protein-related processes.