Per Rugaard Poulsen,Byungchul Cho,Katja Langen,Patrick Kupelian,Paul J. Keall
申请号：
US12584227
公开号：
US08379794B2
申请日:
2009.09.01
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention provides a method for estimation of retrospective and real-time 3D target position by a single imager. The invention includes imaging a target on at least one 2D plane to determine 2D position and/or position components of the target, and resolving a position and/or position component along at least one imager axis of the target using a spatial probability density. The present invention provides a probability-based method for accurate estimation of the mean position, motion magnitude, motion correlation, and trajectory of a tumor from CBCT projections. The applicability of the method for tumors with periodic respiratory motion and for prostate are provided. Clinical feasibility is demonstrated for a pancreas tumor. The method includes monoscopic tracking of the 3D prostate position utilizing the spatial probability density to estimate the unresolved motion from the resolved motion. The method is applicable to prostate tracking even with a population-based probability density.
