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MARBURGVIRUS CONSENSUS ANTIGENS, NUCLEIC ACID CONSTRUCTS AND VACCINES MADE THEREFROM, AND METHODS OF USING SAME
专利权人:
The Trustees of the University of Pennsylvania;THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY
发明人:
David Weiner,Ami Patel,Sarah Elliott
申请号:
US16465691
公开号:
US20190290751A1
申请日:
2017.12.01
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Nucleic acid molecules and compositions comprising one or more nucleic acid sequences that encode a consensus Marburgvirus filovirus glycoprotein immunogens. Immunomodulatory methods and methods of inducing an immune response against Marburgvirus are disclosed. Method of preventing infection by Marburgvirus and methods of treating individuals infected with Marburgvirus are disclosed. Consensus Marburgvirus filovirus glycoprotein immunogens are disclosed.
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